Mechanism
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide derived from epithalamin, a polypeptide extract of the pineal gland. It has demonstrated telomerase activation in somatic cells, normalized circadian melatonin secretion, and antioxidant effects in multiple animal studies. Human clinical data is limited but includes small trials by Khavinson et al.
Indications
Regulatory status
Epitalon has no FDA approval status and sits on the 503A Category 2 list. It is not approved for clinical use in the US. Northline tracks regulatory developments globally.
References
This fact sheet is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Compounded medications are not FDA-approved. Prescribing decisions are made by a licensed clinician based on individual medical necessity. Not all patients qualify.